Capture Efficiency of Magnetically Labeled Particles Traveling Through an Intracranial Aneurysm

Abstract Cell manipulation using external magnetic fields has been proposed to accelerate the neck reendothelization of saccular unruptured stented intracranial aneurysms. This work presents a computational fluid dynamics (CFD) model Saccular Brain Aneurysm that incorporates helicoidal stent. An Eulerian-Lagrangian implemented in ANSYS-Fluent is used simulate hemodynamics aneurysm. In silico studies have conducted describe incidence field direction, frequency and amplitude on blood particle capture efficiency, when an trap magnetically labeled particles traveling through It found direction affects concentration target region. Simulation results show highest efficiency obtained with 1T open bore MRI scanner, permanent magnet used.